Ni-Catalyzed Reductive Difunctionalization of Alkenes

作者:Ping, YY (Ping, Yuanyuan)[ 1 ] ; Kong, WQ (Kong, Wangqing)[ 1 ]

SYNTHESIS-STUTTGART

卷: 52 期: 7 页: 979-992

DOI: 10.1055/s-0039-1690807

出版年: APR 1 2020

文献类型:Review

摘要

Alkene difunctionalization represents one of the most efficient methods to synthesize highly functionalized molecules from simple and readily available starting materials. In contrast to the well-established redox-neutral alkene difunctionalization reactions, reductive alkene difunctionalization, which simultaneously introduces two electrophiles on both sides of the double bond, has been much less developed, especially in enantioselective manner. This review summarizes recent advances in the nickel-catalyzed reductive difunctionalization of alkenes and highlights the enantioselective transformations.

关键词

作者关键词:nickel catalysis; alkene difunctionalization; reductive cross-coupling; enantioselectivity; Heck cyclization

KeyWords Plus:CROSS-COUPLING REACTIONS; ARYL-ALKENYLATION; DICARBOFUNCTIONALIZATION; HALIDES; BROMIDES

作者信息

通讯作者地址:

Wuhan University Wuhan Univ, IAS, CPS, Wuhan 430072, Peoples R China.

通讯作者地址: Kong, WQ (通讯作者)

Wuhan Univ, IAS, CPS, Wuhan 430072, Peoples R China.

地址:

[ 1 ]‎ Wuhan Univ, IAS, CPS, Wuhan 430072, Peoples R China

电子邮件地址:wqkong@whu.edu.cn