报告时间:2017年5月16日(周二)8:30
报告地点:武汉大学高等研究院
报告人:胥国勇
职 务:美国杜克大学,博士后
题 目:Translational Control of Plant Immunity: From Mechanisms to Practice
报告简介:
In the absence of specialized immune cells, the need for plants to reprogram transcription to transition from growth-related activities to defense is well understood. However, little is known about translational changes that occur during immune induction. Using ribosome footprinting (RF), we found that during pattern-triggered immunity (PTI), translational reprogramming is a fundamental layer of immune regulation and further discovered R-motif and upstream open reading frames (uORFs) are important RNA features conferring stringent translational control of defense genes. Those mechanisms contribute to resolve the conflict of compromising plant growth with enhanced resistance. This broadly applicable new strategy may lead to reduced use of pesticides and lightening of selective pressure for resistant pathogens.