Oxidant-Induced Azolation of Electron-Rich Phenol Derivatives

作者:Wang, XY (Wang, Xiaoyu)[ 1 ] ; Wang, SC (Wang, Shengchun)[ 2 ] ; Gao, YM (Gao, Yiming)[ 2 ] ; Sun, H (Sun, He)[ 2 ] ; Liang, XA (Liang, Xing'an)[ 2 ] ; Bu, FX (Bu, Faxiang)[ 2 ] ; Abdelilah, T (Abdelilah, Takfaoui)[ 2 ] ; Lei, AW (Lei, Aiwen)[ 1,2 ]

ORGANIC LETTERS

卷: 22 期: 14 页: 5429-5433

DOI: 10.1021/acs.orglett.0c01796

出版年: JUL 17 2020

文献类型:Article

摘要

Since N-arylazoles are widely present in natural products, pharmaceuticals, and functional materials, it is important to develop a simple and efficient synthetic method for the synthesis of N-arylazoles. Herein, an oxidant-induced intermolecular azolation of phenol derivatives was demonstrated under catalyst-free condition. Both monoazolation and diazolation of phenols can be successfully achieved via this practical and powerful method.

关键词

KeyWords Plus:C-H AMINATION; CATALYZED ARYLATION; PALLADIUM; FUNCTIONALIZATION

作者信息

通讯作者地址:

Jiangxi Normal University Jiangxi Normal Univ, Natl Res Ctr Carbohydrate Synth, Nanchang 330022, Jiangxi, Peoples R China.

Wuhan University Wuhan Univ, Inst Adv Studies IAS, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China.

通讯作者地址: Lei, AW (通讯作者)

Jiangxi Normal Univ, Natl Res Ctr Carbohydrate Synth, Nanchang 330022, Jiangxi, Peoples R China.

通讯作者地址: Lei, AW (通讯作者)

Wuhan Univ, Inst Adv Studies IAS, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China.

地址:

[ 1 ]‎ Jiangxi Normal Univ, Natl Res Ctr Carbohydrate Synth, Nanchang 330022, Jiangxi, Peoples R China

[ 2 ]‎ Wuhan Univ, Inst Adv Studies IAS, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China

电子邮件地址:aiwenlei@whu.edu.cn