Electrochemical oxidative decarboxylation and 1,2-aryl migration towards the synthesis of 1,2-diaryl ethers

作者:Bu, FX (Bu, Faxiang)[ 1 ] ; Lu, LJ (Lu, Lijun)[ 1 ] ; Hu, X (Hu, Xia)[ 1 ] ; Wang, SC (Wang, Shengchun)[ 1 ] ; Zhang, H (Zhang, Heng)[ 1 ] ; Lei, AW (Lei, Aiwen)[ 1,2 ]

CHEMICAL SCIENCE

卷: 11 期: 36 页: 10000-10004

DOI: 10.1039/d0sc03708g

出版年: SEP 28 2020

文献类型:Article

摘要

Carboxylic acid compounds are important chemicals and are widely present in various natural products. They are not only nucleophiles, but also radical precursors. Classic transition-metal-catalyzed and photochemical decarboxylation have shown their excellent site selectivity in radical chemistry. However, electrochemical decarboxylation with a long history hasn't got enough attention in recent years. In this work, the electrochemical oxidative decarboxylation and 1,2-aryl migration of 3,3-diarylpropionic acids have been introduced to construct C-O bonds with alcohols. Remarkably, this transformation can proceed smoothly without metal catalysts and external oxidants.

关键词

KeyWords Plus:ARYLATION; PHOTOREDOX; REARRANGEMENT; KETONES; ACIDS; ELECTROSYNTHESIS; CATALYSIS; ACETATE

作者信息

通讯作者地址:

Wuhan University Wuhan Univ, Coll Chem & Mol Sci, Inst Adv Studies IAS, Wuhan 430072, Hubei, Peoples R China.

Jiangxi Normal University Jiangxi Normal Univ, Natl Res Ctr Far Carbohydrate Synth, Nanchang 330022, Jiangxi, Peoples R China.

通讯作者地址: Zhang, H; Lei, AW (通讯作者)

Wuhan Univ, Coll Chem & Mol Sci, Inst Adv Studies IAS, Wuhan 430072, Hubei, Peoples R China.

通讯作者地址: Lei, AW (通讯作者)

Jiangxi Normal Univ, Natl Res Ctr Far Carbohydrate Synth, Nanchang 330022, Jiangxi, Peoples R China.

地址:

[ 1 ]‎ Wuhan Univ, Coll Chem & Mol Sci, Inst Adv Studies IAS, Wuhan 430072, Hubei, Peoples R China

[ 2 ]‎ Jiangxi Normal Univ, Natl Res Ctr Far Carbohydrate Synth, Nanchang 330022, Jiangxi, Peoples R China

电子邮件地址:hengzhang@whu.edu.cn; aiwenlei@whu.edu.cn