Nickel-catalyzed enantioselective electroreductive cross-couplings

作者:Zhou, ZJ (Zhou, Zhijun)[ 1 ] ; Xu, S (Xu, Sheng)[ 1 ] ; Zhang, J (Zhang, Jing)[ 1 ] ; Kong, WQ (Kong, Wangqing)[ 1 ]

ORGANIC CHEMISTRY FRONTIERS

卷: 7 期: 20 页: 3262-3265

DOI: 10.1039/d0qo00901f

出版年: OCT 21 2020

文献类型:Editorial Material

摘要

Ni-Catalyzed reductive cross-coupling of two electrophiles has recently evolved into a powerful means for building diverse carbon-carbon bonds in an enantioselective manner. However, this strategy usually requires the use of excessive metal powder as a reducing agent, which poses severe challenges with respect to reproducibility and sustainability. Electrochemical cathode reduction provides new opportunities for reductive cross-coupling reaction in an environmentally benign manner. In this highlight, we summarize the recent progress in Ni-catalyzed enantioselective electroreductive coupling reactions.

关键词

KeyWords Plus:SYNTHETIC ORGANIC ELECTROCHEMISTRY; HALIDES; ELECTROSYNTHESIS; PRINCIPLES; OXIDATION

作者信息

通讯作者地址:

Wuhan University Wuhan Univ, Inst Adv Studies IAS, Wuhan 430072, Hubei, Peoples R China.

通讯作者地址: Zhang, J; Kong, WQ (通讯作者)

Wuhan Univ, Inst Adv Studies IAS, Wuhan 430072, Hubei, Peoples R China.

地址:

[ 1 ]‎ Wuhan Univ, Inst Adv Studies IAS, Wuhan 430072, Hubei, Peoples R China

电子邮件地址:jzhangwhu@whu.edu.cn; wqkong@whu.edu.cn