Wu, JW (Wu, Jiwei)^{[ 1 ]} ; Zhou, YC (Zhou, Yuchen)^{[ 1 ]} ; Wu, T (Wu, Ting)^{[ 1 ]} ; Zhou, Y (Zhou, Yi)^{[ 1 ]} ; Chiang, CW (Chiang, Chien-Wei)^{[ 1 ]} ; Lei, AW (Lei, Aiwen)^{[ 1,2 ]}

A novel method of palladium-catalyzed oxidative carbonylation of ketones, amines, and carbon monoxide for the synthesis of 4-quinolones has been developed. This protocol provides a straightforward route to construct useful 4-quinolone derivatives from inexpensive chemicals.

KeyWords Plus:C-H BONDS; DEALKYLATIVE CARBONYLATION; GREEN CHEMISTRY; ATOM ECONOMY; METAL-FREE; DERIVATIVES; ANILINES; 2-ARYL-4-QUINOLONES; OPTIMIZATION; CYCLIZATION

通讯作者地址: Lei, AW (通讯作者)

Wuhan Univ, Coll Chem & Mol Sci, IAS, Wuhan 430072, Peoples R China.

Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China.

地址:

电子邮件地址:aiwenlei@whu.edu.cn

原文PDF链接：

https://pubs.acs.org/doi/10.1021/acs.orglett.7b03337