Peng, L (Peng, Long)^{[ 1 ]} ; Li, YQ (Li, Yuqiang)^{[ 1 ]} ; Li, YY (Li, Yangyang)^{[ 1 ]} ; Wang, W (Wang, Wang)^{[ 1 ]} ; Pang, HL (Pang, Hailiang)^{[ 1 ]} ; Yin, GY (Yin, Guoyin)^{[ 1 ]}

1,1-Diarylalkanes are important structural frameworks which are widespread in biologically active molecules. Herein, we report a reductive relay cross-coupling of alkyl bromides with aryl bromides by nickel catalysis with a simple nitrogen-containing ligand. This method selectively affords 1,1-diarylalkane derivatives with good to excellent yields and regioselectivity.

作者关键词:alkyl electrophiles; beta-hydride elimination; 1,1-diarylalkanes; migratory cross-coupling; high-valent nickel

KeyWords Plus:UNACTIVATED TERTIARY ALKYL; NEGISHI ARYLATIONS; HALIDES; ELECTROPHILES; REMOTE; FUNCTIONALIZATION; SECONDARY; 1,1-DIARYLALKANES; CARBOXYLATION; DIARYLALKANES

通讯作者地址: Yin, GY (通讯作者)

Wuhan Univ, Inst Adv Studies, Wuhan 430072, Hubei, Peoples R China.

地址:

电子邮件地址:yinguoyin@whu.edu.cn

原文PDF链接：

https://pubs.acs.org/doi/pdf/10.1021/acscatal.7b03388