Wen, JW (Wen, Jiangwei)^{[ 1 ]} ; Tang, S (Tang, Shan)^{[ 1 ]} ; Zhang, F (Zhang, Fan)^{[ 1 ]} ; Shi, RY (Shi, Renyi)^{[ 1 ]} ; Lei, AW (Lei, Aiwen)^{[ 1,2 ]}

An efficient palladium/copper CO-catalyzed oxidative double C(sp(2))-H functionalization/carbonylation of diphenyl-amines for synthesis of acridones has been developed. This method utilizes readily available starting materials :and mild reaction conditions. The protocol provides a simple; efficient, and atom economic way to access acridones. Notably the present protocol has excellent functional group tolerance and application value.

KeyWords Plus:BIOLOGICAL-ACTIVITIES; SODIUM PERSULFATE; O-AMINOBENZOATES; ORTHO-ARYLATION; BOND FORMATIONS; SIMPLE ARENES; DERIVATIVES; ACTIVATION; XANTHONES; ALKALOIDS

通讯作者地址: Lei, AW (通讯作者)

Wuhan Univ, Coll Chem & Mol Sci, Inst Adv Studies, Wuhan 430072, Hubei, Peoples R China.

Chinese Acad Sci, Lanzhou Inst Chem Phys, Conducted & State Key Lab Oxo Synth & Select Oxid, Lanzhou 730000, Peoples R China.

地址:

电子邮件地址:aiwenlei@whu.edu.cn

原文PDF链接：

https://pubs.acs.org/doi/10.1021/acs.orglett.6b03356