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陈世贵

作者:     点击:      时间:2018-10-08

                                     

                                    陈世贵

教授,博士生导师

国家青年千人计划入选者(第十三批)

邮箱:sgchen@whu.edu.cn

研究方向

1.超分子检测体系:针对特定毒性物质(如神经毒剂等)的识别体系的设计,以及器件的研发

2.响应超分子材料:通过自组装构建响应型超分子材料,研究其在靶向药物载体等方向的应用

3.超分子催化:通过自组装高效构建催化体系,结合底物识别,发展仿酶催化

导师介绍

教育与工作经历

2017.01-至今 武汉大学高等研究院,教授

2012.01-2016.12美国俄亥俄州立大学博士后,导师:Prof. Jovica D. Badjić

2011.01-2011.12中国科学院上海有机化学研究所研究助理,导师:黎占亭、赵新研究员

2005.09-2010.12中国科学院上海有机化学研究所博士,导师:蒋锡夔院士、黎占亭研究员

2001.09-2005.07南开大学,材料化学,理学学士

代表性论文

1.Wang, L., Neal, T.;Chen, S. G.*; Badjić, J. D.*,Multivalent and Photoresponsive Assembly of Dual-Cavity Baskets in Water,Chem. Eur. J.2017,23, 8829-8833.

2.Chen, S. G.[+]; Wang, L.[+], Polen, S.; Badjić, J. D.*, On Gating the Trafficking of Molecules across Vesicular Membrane Composed of Dual-Cavity Baskets.Chem. Mater.2016,28, 8128–8131. ([+]These authors contributed equally to this project.)

3.Chen, S. G.; Polen, S.; Wang, L., Yamasaki, M.; Hadad, C. M.; Badjić, J. D.*, On Two-Dimensional Supramolecular Polymers Embodying Large Unilamellar Vesicles in Water.J. Am. Chem.Soc. 2016,138, 11312-11317.

4.Chen, S. G., Zhao, Z. X., Jiang, X. N., Wang, L., Zhou, T. Y., Lu, C. L., Zhao, X.,*, Jiang, X. K., Ma, Y. G.,* Wang, R. X.,* Li, Z. T.*, Temperature-Responsive Chiral (A)6B Supram olecu lar Cages Based on Conformational Preferences,Chem.-Asian J.2016,11, 465−469.

5.Chen, S. G.; Yamasaki, M.; Polen, S.; Gallucci, J.; Hadad, C. M.; Badjić, J. D.*, Dual-Cavity Baskets Promote Encapsulation in Water in an Allosteric Fashion. J. Am. Chem. Soc.2015,137, 12276−12281.

6.Chen, S. G.; Ruan, Y.; Brown, J. D.; Hadad, C. M.; Badjić, J. D.*, The Recognition Characteristics of Adaptive Assemblies of Amphiphilic Baskets for Selective Detection and Mitigation of Toxic Nerve Agents.J. Am. Chem. Soc.2014,136, 17337–17342.

7. Chen, S. G.; Ruan, Y.; Brown, J. D.; Gallucci, J.; Maslak, V.; Hadad, C. M.; Badjić, J. D.*, Assembly of Amphiphilic Baskets into Stimuli-Responsive Vesicles. Developing a Strategy for the Detection of Organophosphorus Chemical Nerve Agents. J. Am. Chem. Soc.2013,135, 14964-14967.

8. You, L. Y.[+];Chen, S. G.[+];Zhao, X.*; Liu, Y.; Lan, W. X.; Zhang, Y.; Lu, H. J.; Cao, C. Y.; Li, Z. T.*, C‒H•••O Hydrogen Bonding Induced Triazole Foldamers: Efficient Halogen Bonding Receptors for Organohalogens. Angew. Chem. Int. Edit.2012,51, 1657-1661.([+]These authors contributed equally to this project.)

9.Chen, S. G.; Yu, Y.; Zhao, X.*; Ma, Y. G.*; Jiang, X. K.; Li, Z. T.*, Highly Stable Chiral (A)6-B Supramolecular Copolymers: A Multivalency-Based Self-Assembly Process.J. Am. Chem.Soc. 2011,133, 11124-11127.

10.Chen, S. G.; Fu, Y. C.; Wang, G. T.; Li, G. Y.; Ma, Y. G.*; Jiang, X. K.; Li, Z. T.*, Chiral Eighteen-Component Three-Dimensional Supramolecular Entities Stabilized by the Hydrogen Bonding and Coordination Interactions. Tetrahedron2010,66, 4057-4062.

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